As of 2010, San Antonio does not require a license to do business. If you intend to open a business in San Antonio, however, you need a permit from the Department of Development Services. In some cases, you may need to submit to an inspection of your business location.

Contact the Internal Revenue Service and request an Employer Identification Number if your business plans to operate with employees or as a partnership or corporation. Call 1-800-829-4933 or apply online.

Fill out the tax registration form online to get a Texas sales tax permit.

Call the San Antonio Development Services Department at 210-207-1111 to request an application for a business permit. Ask for an appointment for an initial site inspection, if this has never been completed for your business location.

Complete the application for your business permit. Submit the application by mail or in person to:

San Antonio Development Services Department 1901 S. Alamo St. San Antonio TX 78204